Liora · Journal · Well-Aging
The case for starting earlier and doing less
Holding on to collagen is cheaper, gentler and more convincing than replacing it. Which makes the best time to start a decade before most people think about it.
There is an awkward fact at the centre of aesthetic dermatology: almost everything is easier to keep than to get back.
Collagen production begins declining in the twenties and the loss compounds. Elastin, once it is damaged, is not meaningfully replaced at all. Pigment accumulates from exposure that happened decades before it becomes visible. Every one of those is a slow process, and slow processes respond far better to being slowed further than to being reversed.
What this does not mean
It does not mean treating a twenty-five-year-old face as though it needs correcting. The industry’s version of starting early is selling filler to people who have nothing yet to fill, and that is how you get the faces everyone can spot.
Starting early means something narrower and duller: sunscreen used properly, a retinoid tolerated and kept up, pigment treated while it is superficial, and collagen-stimulating treatment at intervals long enough that nobody watching could tell you were having anything done.
What it looks like by decade
In the twenties, almost all of the available benefit is in protection and in treating acne before it scars. Scarring is permanent and acne is not, which makes that the highest-leverage treatment in dermatology for that age group.
In the thirties, pigment and the first fine lines. This is where a retinoid earns its reputation and where melasma, if it is going to appear, usually does. Treated at this stage it is a surface problem. Left, it becomes a dermal one, which is a different and much harder conversation.
In the forties, firmness. Energy-based treatment works best while there is still collagen to stimulate, which is an argument for starting it before the laxity is obvious rather than after.
In the fifties and beyond, the work shifts from prevention to maintenance, and skin health — barrier, dryness, itch, sun damage, screening — becomes as much of the appointment as appearance.
What actually has evidence behind it
It is worth separating the things that are well established from the things that are merely sold. Three interventions have the weight of evidence behind them, and all three are unglamorous.
Sunscreen, used properly. Daily broad-spectrum use is the single best-evidenced anti-aging intervention there is, and the qualifier is doing real work — most people apply roughly a quarter of the amount the label was tested at, and almost nobody reapplies.
A retinoid, tolerated. The most studied topical in dermatology, with decades of data on fine lines, pigment and collagen. The word that matters is tolerated: a retinoid used three nights a week for ten years does far more than a stronger one abandoned in a fortnight because the skin peeled.
Not smoking. Unwelcome, well documented, and larger in effect than anything available in the clinic.
Everything beyond those three is genuinely useful and genuinely secondary. A practice that sells you the secondary things while skipping the first three has the order wrong.
The practical version
Less, more often, starting sooner. A small amount of treatment spread across years reads as good health. The same total amount delivered in one intensive afternoon reads as work, because the face changed faster than the person did.
That is the entire argument, and it is also the reason the first consultation is mostly questions. What is worth doing depends on where you are starting from and how long you are prepared to take, and the second of those is a conversation rather than a diagnosis.